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 Formulary Chapter 10: Musculoskeletal and joint diseases - Full Chapter
10.01.03  Expand sub section  Drugs which suppress the rheumatic disease process
10.01.03  Expand sub section  Gold
10.01.03  Expand sub section  Penicillamine
10.01.03  Expand sub section  Antimalarials
10.01.03  Expand sub section  Drugs affecting the immune response to top
Abatacept
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Formulary
Red
High Cost Medicine

Infusion and subcutaneous injection

 
Link  NICE TA373: Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis
Link  NICE TA375: Rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
   
Adalimumab (Imraldi Amgevita Humira )
(injection )
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Formulary
Red
High Cost Medicine
 
Link  NICE TA195: Rheumatoid arthritis - after failure of a TNF inhibitor
Link  NICE TA199: Psoriatic arthritis
Link  NICE TA373: Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis
Link  NICE TA375: Rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
Link  NICE TA383: TNF-alpha inhibitors for ankylosing spondylitis and non-radiographic axial spondyloarthritis
   
Anakinra (Kineret)
(Secondary Care only)
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Restricted Drug Restricted
Red
High Cost Medicine
 
   
Cytotoxic Drug Azathioprine tablets
(rheumatology)
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Formulary
Amber with Shared Care
 
Link  Shared care guidelines Immune modulating therapies June 2019
   
Baricitinib tablets (Olumiant)
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Red
High Cost Medicine
 
Link  TA 466 Baricitinib for moderate to severe rheumatoid arthritis
   
Belimumab (Benlysta )
(for infusion)
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Formulary
Red
High Cost Medicine
 
Link  NICE TA397: Belimumab for treating active autoantibody-positive systemic lupus erythematosus
   
Certolizumab Pegol
(injection )
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Formulary
Red
High Cost Medicine
 
Link  NICE TA375: Rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
Link  NICE TA383: TNF-alpha inhibitors for ankylosing spondylitis and non-radiographic axial spondyloarthritis
Link  NICE TA415 Certolizumab pegol for treating rheumatoid arthritis after inadequate response to a TNF-alpha inhibitor
Link  NICE TA445 Certolizumab pegol and secukinumab for psoriatic arthritis after inadequate response to DMARDs
Link  NICE TA574 Certolizumab pegol for treating moderate to severe plaque psoriasis
   
Etanercept (Enbrel)
(injection )
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Formulary
Red
High Cost Medicine

Prescribe by brand name

 
Link  NICE TA35: Adult psoriasis
Link  NICE TA195: Rheumatoid arthritis after the failure of a TNF inhibitor
Link  NICE TA199: Psoriatic arthritis
Link  NICE TA373: Abatacept, adalimumab, etanercept and tocilizumab for JIA
Link  NICE TA375: Rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
Link  NICE TA383: TNF-alpha inhibitors for ankylosing spondylitis and non-radiographic axial spondyloarthritis
   
Etanercept biosimilar (Benepali)
(injection )
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Formulary
Red

Prescribe by brand name

 
Link  NICE TA35: Adult psoriasis
Link  NICE TA195: rheumatoid arthritis after the failure of a TNF inhibitor
Link  NICE TA199: Psoriatic arthritis
Link  NICE TA375: Rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
Link  NICE TA383: TNF-alpha inhibitors for ankylosing spondylitis and non-radiographic axial spondyloarthritis
   
Golimumab (Simponi)
(injection )
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Formulary
Red
High Cost Medicine
 
Link  NICE TA220: psoriatic arthritis
Link  NICE TA497: Golimumab for treating non-radiographic axial spondyloarthritis
Link  NICE TA375: Rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
Link  NICE TA383: TNF-alpha inhibitors for ankylosing spondylitis and non-radiographic axial spondyloarthritis
   
Infliximab (Remicade)
(for infusion)
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Formulary
Red
High Cost Medicine

Prescribe by brand name

 
Link  NICE TA195: Rheumatoid arthritis (after failure of a TNF inhibitor)
Link  NICE TA199: Psoriatic arthritis
Link  NICE TA375: Rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
Link  NICE TA383: TNF-alpha inhibitors for ankylosing spondylitis and non-radiographic axial spondyloarthritis
   
Infliximab biosimilar (Inflectra)
(for infusion)
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Formulary
Red

Prescribe by brand name

 
   
Infliximab biosimilar (Remsima)
(for infusion)
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Formulary
Red

Prescribe by brand name

 
   
Leflunomide tablets
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Formulary
Amber with Shared Care
NOT FOR RENAL INDICATIONS 
Link  Shared care guidelines Immune modulating therapies June 2019
   
Cytotoxic Drug Methotrexate
(rheumatology)
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Formulary
Amber with Shared Care

Tablets 2.5mg


Nordimet   - prefilled pen


Metoject PEN - prefilled pen


 

 
Link  Shared care guideline Immune modulating therapies June 2019
   
Rituximab (MabThera, Truxima)
(for infusion)
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Formulary
Red
High Cost Medicine

For SLE refer to NHSE policy

 
Link  NICE TA 308 - ANCA vasculitis
Link  NICE TA195: Rheumatoid arthritis - after failure of a TNF inhibitor
   
Sarilumab  (Kevzara )
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Formulary
Red
High Cost Medicine

For use in line with NICE TA485 

 
Link  NICE TA485: Sarilumab for moderate to severe rheumatoid arthritis
   
Secukinumab injection (Cosentyx)
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Formulary
Red
 
Link  NICE TA 407 Secukinumab for active ankylosing spondylitis after treatment with non-steroidal anti-inflammatory drugs or TNF-alpha inhibitors
Link  NICE TA 445 Certolizumab pegol and secukinumab for psoriatic arthritis after inadequate response to DMARDs
   
Tocilizumab (RoActemra)
(for infusion)
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Formulary
Red
High Cost Medicine
 
Link  NICE TA247:Tocilizumab in RA
Link  NICE TA373: Abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis
Link  NICE TA375: Rheumatoid arthritis not previously treated with DMARDs or after conventional DMARDs only have failed
Link  NICE TA 518 Tocilizumab for treating giant cell arteritis
   
Tofacitinib  (Xeljanz)
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Formulary
Red
High Cost Medicine
 
Link  NICE TA480: tofacitinib for moderate to severe rheumatoid arthritis
Link  NICE TA543 Tofacitinib for treating active psoriatic arthritis after inadequate response to DMARDs
   
Ustekinumab
(injection )
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Formulary
Red
 
Link  NICE TA 340 Ustekinumab for treating active psoriatic arthritis
   
Leflunomide tablets
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Restricted Drug Restricted
Red

For the treatment of BK viraemia and nephropathy in renal transplant recipients

 
   
10.01.03  Expand sub section  Cytokine modulators
10.01.03  Expand sub section  Sulfasalazine
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Green

Primary and Secondary Care (unrestricted) may be prescribed by GPs, hospital doctors or other qualified prescribers in primary and secondary care  

Amber Initiation

Amber Initiated: first prescription from specialist, on going supplies from primary care (or when stabilised on therapy).  

Amber Recommended

Amber recommended: first prescription may be supplied by primary care under the advice of a specialist.  

Amber with Shared Care

For initiation within a specialist service followed by ongoing prescribing in primary care according to published shared care guidance  

Red

For initiation and ongoing prescribing in secondary care only. Medicines in this category may be further restricted to use by specific hospital departments only.  

Blue

For prescribing in primary care only  

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