netFormulary Portsmouth and South East Hampshire NHS
Prescribing Formulary  
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 Formulary Chapter 3: Respiratory system - Full Chapter
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03.07  Expand sub section  Mucolytics
Acetylcysteine injection
(Mucolytic)
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Restricted Drug Restricted
Red

Administered via nebuliser as a mucolytic  - refer to PHT Drug Therapy Guideline 107.03

 
   
Carbocisteine
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Formulary
Green

Capsules 375mg and syrup 250mg in 5ml


Oral solution 750mg in 10ml sachets are a cost-effective option if liquid is required.

 
   
Ivacaftor
(Kalydeco)
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Formulary
Red
High Cost Medicine
NHS England

As per NHS England commissioning statement Cystic Fibrosis Modulator Therapies 19013P

 
   
Lumacaftor/Ivacaftor (Orkambi®)
(film coated tablets)
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Formulary
Red
High Cost Medicine
NHS England

As per NHS England commissioning statement Cystic Fibrosis Modulator Therapies 190137P

 
   
Tezacaftor/Ivacaftor (Symkevi®)
(film coated tablets)
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Red
High Cost Medicine
NHS England

NHS England commissioning statement Cystic Fibrosis Modular Therapies 190137P

 
   
03.07  Expand sub section  Dornase alfa
Dornase Alfa (Pulmozyme®)
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Formulary
Red
High Cost Medicine

Cystic fibrosis  -  commissioned by NHS England

 
Link  NHSE Policy A01/P/b Inhaled Therapy for Adults and Children with Cystic Fibrosis
   
03.07  Expand sub section  Hypertonic Sodium Chloride
Sodium chloride 3% (Hypertonic) (MucoClear®)
(for nebulisation)
 Track Changes
Formulary
Red

Paediatrics only – bronchiolitis

 
   
Sodium chloride 7% (Hypertonic)
(for nebulisation)
 Track Changes
Formulary
Amber Initiation

Cystic fibrosis - adults and children. Refer to Drug Tariff for products prescribable on FP10

 
   
 ....
 Non Formulary Items
Erdosteine  (Erdotin®)

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Non Formulary
 
Lumacaftor + Ivacaftor  (Orkambi®)

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Non Formulary
Link  NICE TA398: Lumacaftor–ivacaftor for treating cystic fibrosis homozygous for the F508del mutation
 
Mecysteine  (Visclair®)

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Non Formulary
 
Sodium chloride 6% (hypertonic)  (MucoClear®)

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Green

Primary and Secondary Care (unrestricted) – may be prescribed by GPs, hospital doctors or other qualified prescribers in primary and secondary care  

Amber Initiation

Amber Initiated: first prescription from specialist, on going supplies from primary care (or when stabilised on therapy).  

Amber Recommended

Amber recommended: first prescription may be supplied by primary care under the advice of a specialist.  

Amber with Shared Care

For initiation within a specialist service followed by ongoing prescribing in primary care according to published shared care guidance  

Red

For initiation and ongoing prescribing in secondary care only. Medicines in this category may be further restricted to use by specific hospital departments only.  

Blue

For prescribing in primary care only  

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